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Tobramycin_DataSheet_MedChemExpress

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Inhibitors, Agonists, Screening Libraries

Data Sheet

BIOLOGICAL ACTIVITY:

Tobramycin is an aminoglycoside, broad–spectrum antibiotic produced by Streptomyces tenebrarius.

Target: Antibacterial

Tobramycin is an aminoglycoside antibiotic derived from Streptomyces tenebrarius and used to treat various types of bacterial infections, particularly Gram–negative infections. It is especially effective against species of Pseudomonas [1].

Tobramycin works by binding to a site on the bacterial 30S and 50S ribosome, preventing formation of the 70S complex. As a result,mRNA cannot be translated into protein and cell death ensues. Tobramycin is preferred over gentamicin for Pseudomonas aeruginosa pneumonia due to better lung penetration. From Wikipedia [2].

References:

[1]. http://www.toku–/Upload/Products/PDS/20120515001224.pdf

[2]. /wiki/Tobramycin

Product Name:

Tobramycin Cat. No.:

HY-B0441CAS No.:

32986-56-4Molecular Formula:

C 18H 37N 5O 9Molecular Weight:

467.51Target:

Bacterial Pathway:

Anti–infection Solubility:H 2

O: ≥ 200 mg/mL

Caution: Product has not been fully validated for medical applications. For research use only.

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