慢性荨麻疹过敏原检测的临床意义及可能的病因分析_高广程
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点:第一,所切取的皮瓣应包含掌背动脉,在此操作过程中可以将两个手指伸肌腱作为解剖标准;第二,切取皮瓣的过程中尽可能采用明道转移,避免造成压迫;第三,皮瓣游离后应放松止血带,待认真观察确定安全后再进行皮瓣转移;第四,术后缝合需要注意丝线选择,科学选择固定方面,并进行必要的常规护理及酌情给予抗炎和抗血栓等药物治疗。
虽然显微外科技术具有明显的优势,但根据本人多年的手术经验及相关报道[10-11],显微外科技术治疗小儿先天性并指畸形,也存在一些需要密切注意事项:第一,手术过程中对医师操作技巧要求较高;第二,由于在显微镜下景深有时会略有上下移动,对手术医师的手术素养要求高;第三,手术显微镜无选择性放大视野范围内的一切事物,肉眼所不能看见的抖动在显微镜下却很显著,可能会影响手术操作。因此,笔者建议手术操刀医师需要进行专门的训练,经过一段时期的训练和适应过程,待熟练掌握手术全部操作后方可进行临床手术。4结论
综述所述,经验丰富的医师采用显微外科技术治疗小儿先天性并指畸形具有很高的应用价值,对改善患儿患指的外观和功能、降低并发症发生率具有明显的效果。参考文献
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(收稿日期:2015-03-17)
DOI:10.3969/j.issn.1671-4695.2015.014.025文章编号:1671-4695(2015)014-1207-04
慢性荨麻疹过敏原检测的临床意义及可能的病因分析
高广程1许颖2(首都医科大学附属北京友谊医院1皮肤性病科;2检验科北京100050)
【摘要】目的探讨过敏原检测对慢性荨麻疹诊疗的临床意义,同时分析慢性荨麻疹的可能致病因素。方法对临床确诊485例慢性荨麻诊患者采用德国Allergy Screen变应原定量免疫印迹法检测血清过敏原及总IgE,检测血常规。对慢性荨麻诊可能的病因进行分析。结果169例(34.85%)患者过敏原阳性;总IgE水平>100IU/ml者占241例(49.69%)。过敏原检出阳性率较低,慢性荨麻疹病因复杂,除外过敏原致敏外还有许多发病因素。结论开展过敏原检测在慢性荨麻疹诊治中的作用是有限的,病史的询问在寻找慢性荨麻疹的可能的原因或诱因中起重要作用。
【关键词】慢性荨麻诊过敏原IgE免疫印迹临床分型病因分析
Study on the clinical significance of allergen testing in diagnosis of chronic urticaria and analysis of possible pathogens.GAO Guang-cheng1,XU Ying2.1Department of Dermatology;2Clinical laboratory,Beijing Friendship Hospital,Capital Medical University,Beijing100050,China.
【Abstract】Objective To explore the clinical significance of allergen testing for chronic urticaria(CU),at the same time to discuss the possible pathogenic factors of CU.Methods The serum allergens and serum levels of total IgE of485patients with CU were detected by German allergy screen immunoblotting method.Some patients had taken blood routine examination.Review of literatures on causes of CU had also been carried out.Results The positive rate of tests was34.85%(169patients).The total IgE level(>100IU/mL)was positive in241patients (49.69%).The positive rate of allergen test was low,and the etiology of CU was complex,There are many pathogenic factors besides the allergen sensitization.Conclusion The importance of detection of allergens for pathogenesis of CU is limited,and the history inquiries for searching the causes of CU may play an important role.
【Key words】Chronic urticaria;Allergen;IgE;Immunoblotting;Clinical classification;Pathogeny analysis